Molecular biotechnology : principles and applications of recombinant DNA / Bernard R. Glick and Jack J. Pasternak, Cheryl L. Patten.

Includes bibliographical references and index.

The development of molecular biotechnology -- DNA, RNA, and protein synthesis -- Recombinant DNA technology -- Chemical synthesis, amplification, and sequencing of DNA -- Bioinformatics, genomics, and proteomics -- Manipulation of gene expression in prokaryotes -- Heterologous protein production in eukaryotic cells -- Directed mutagenesis and protein engineering -- Molecular diagnostics -- Protein therapeutics -- Nucleic acids as therapeutic agents -- Vaccines -- Synthesis of commercial products by recombinant microorganisms -- Bioremediation and biomass utilization -- Plant growth-promoting bacteria -- Microbial insecticides -- Large-scale production of proteins from recombinant microorganisms -- Genetic engineering of plants : methodology -- Engineering plants to overcome biotic and abiotic stress -- Engineering plant quality and proteins -- Transgenic animals -- Regulating the use of biotechnology -- Societal issues in biotechnology.

Acclaimed by students and instructors, "Molecular Biotechnology: Principles and Applications of Recombinant DNA" is now in its fourth edition, bringing it thoroughly up to date with the latest findings and the latest industrial, agricultural, pharmaceutical, and biomedical applications. At the same time, the text maintains all the hallmarks that have made it a bestseller. These include its straightforward, jargon-free writing style and its extensive use of figures that help students make sense of complex biological systems and processes. These features not only enable students to grasp core concepts, but also create the foundation needed to support their own research and development work using recombinant DNA technology. This fourth edition features greatly expanded coverage of the latest innovations in DNA sequencing techniques, therapeutics, vaccines, transgenic plants, and transgenic animals. Moreover, readers will find nearly 240 new figures to help them grasp all the latest concepts and applications. With its broad range of topics, Molecular Biotechnology is adaptable to different upper-level undergraduate and graduate courses emphasizing particular aspects of modern biotechnology. For example, instructors can easily tailor the content to courses focusing on the fundamentals of biotechnology as well as courses dedicated to medical, agricultural, environmental, or industrial applications. New edition presents 645 figures and 113 tables throughout the text, hundreds of which illustrate complex systems and processes. It includes chapter summaries highlighting key points. It contains references to the literature in each chapter facilitating detailed investigations of all topics covered in the text. It features end-of-chapter review questions enabling students to assess their knowledge. There are updated examples illustrating the latest concepts and applications.

Dawson